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HOXC8 regulates self-renewal, differentiation and transformation of breast cancer stem cells
BACKGROUND: Homeobox genes are master regulators of cell fate during embryonic development and their expression is altered in cancer. By regulating the balance between cell proliferation and differentiation, they maintain homeostasis of normal tissues. Here, we screened the expression of homeobox ge...
Autores principales: | Shah, Mansi, Cardenas, Ryan, Wang, Belinda, Persson, Jenny, Mongan, Nigel P., Grabowska, Anna, Allegrucci, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312582/ https://www.ncbi.nlm.nih.gov/pubmed/28202042 http://dx.doi.org/10.1186/s12943-017-0605-z |
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