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Next-generation sequencing in familial breast cancer patients from Lebanon

BACKGROUND: Familial breast cancer (BC) represents 5 to 10% of all BC cases. Mutations in two high susceptibility BRCA1 and BRCA2 genes explain 16–40% of familial BC, while other high, moderate and low susceptibility genes explain up to 20% more of BC families. The Lebanese reported prevalence of BR...

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Detalles Bibliográficos
Autores principales: Jalkh, Nadine, Chouery, Eliane, Haidar, Zahraa, Khater, Christina, Atallah, David, Ali, Hamad, Marafie, Makia J., Al-Mulla, Mohamed R., Al-Mulla, Fahd, Megarbane, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312584/
https://www.ncbi.nlm.nih.gov/pubmed/28202063
http://dx.doi.org/10.1186/s12920-017-0244-7