A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinomas (PDACs) constitutively express the G-protein-coupled cholecystokinin B receptor (CCKBR). In this study, we identified DNA aptamers (APs) that bind to the CCKBR and describe their characterization and targeting efficacy. Using dual SELEX selection against “exposed” C...

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Detalles Bibliográficos
Autores principales: Clawson, Gary A., Abraham, Thomas, Pan, Weihua, Tang, Xiaomeng, Linton, Samuel S., McGovern, Christopher O., Loc, Welley S., Smith, Jill P., Butler, Peter J., Kester, Mark, Adair, James H., Matters, Gail L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312616/
https://www.ncbi.nlm.nih.gov/pubmed/27754762
http://dx.doi.org/10.1089/nat.2016.0621

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