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Deep brain stimulation of the periaqueductal gray releases endogenous opioids in humans

Deep brain stimulation (DBS) of the periaqueductal gray (PAG) is used in the treatment of severe refractory neuropathic pain. We tested the hypothesis that DBS releases endogenous opioids to exert its analgesic effect using [(11)C]diprenorphine (DPN) positron emission tomography (PET). Patients with...

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Detalles Bibliográficos
Autores principales:	Sims-Williams, Hugh, Matthews, Julian C., Talbot, Peter S., Love-Jones, Sarah, Brooks, Jonathan CW, Patel, Nikunj K., Pickering, Anthony E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312788/ https://www.ncbi.nlm.nih.gov/pubmed/27554530 http://dx.doi.org/10.1016/j.neuroimage.2016.08.038

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