RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation

Chikungunya virus (CHIKV) is an arthritogenic alphavirus causing epidemics of acute and chronic arthritic disease. Herein we describe a comprehensive RNA-Seq analysis of feet and lymph nodes at peak viraemia (day 2 post infection), acute arthritis (day 7) and chronic disease (day 30) in the CHIKV ad...

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Detalles Bibliográficos
Autores principales: Wilson, Jane A. C., Prow, Natalie A., Schroder, Wayne A., Ellis, Jonathan J., Cumming, Helen E., Gearing, Linden J., Poo, Yee Suan, Taylor, Adam, Hertzog, Paul J., Di Giallonardo, Francesca, Hueston, Linda, Le Grand, Roger, Tang, Bing, Le, Thuy T., Gardner, Joy, Mahalingam, Suresh, Roques, Pierre, Bird, Phillip I., Suhrbier, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312928/
https://www.ncbi.nlm.nih.gov/pubmed/28207896
http://dx.doi.org/10.1371/journal.ppat.1006155

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