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Structural and Molecular Evidence Suggesting Coronavirus-driven Evolution of Mouse Receptor

Hosts and pathogens are locked in an evolutionary arms race. To infect mice, mouse hepatitis coronavirus (MHV) has evolved to recognize mouse CEACAM1a (mCEACAM1a) as its receptor. To elude MHV infections, mice may have evolved a variant allele from the Ceacam1a gene, called Ceacam1b, producing mCEAC...

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Detalles Bibliográficos
Autores principales:	Peng, Guiqing, Yang, Yang, Pasquarella, Joseph R., Xu, Liqing, Qian, Zhaohui, Holmes, Kathryn V., Li, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313091/ https://www.ncbi.nlm.nih.gov/pubmed/28035001 http://dx.doi.org/10.1074/jbc.M116.764266

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