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YopE specific CD8(+) T cells provide protection against systemic and mucosal Yersinia pseudotuberculosis infection

Prior studies indicated that CD8(+) T cells responding to a surrogate single antigen expressed by Y. pseudotuberculosis, ovalbumin, were insufficient to protect against yersiniosis. Herein we tested the hypothesis that CD8(+) T cells reactive to the natural Yersinia antigen YopE would be more effect...

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Detalles Bibliográficos
Autores principales: González-Juarbe, Norberto, Shen, Haiqian, Bergman, Molly A., Orihuela, Carlos J., Dube, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313184/
https://www.ncbi.nlm.nih.gov/pubmed/28207901
http://dx.doi.org/10.1371/journal.pone.0172314