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The therapeutic potential of HIF-2 antagonism in renal cell carcinoma
Hypoxia, the insufficient delivery of oxygen for the demand of a tissue, contributes to the development of an aggressive phenotype, resistance to radiation therapy and chemotherapy, and is predictive of a poor outcome in numerous tumor types. Adaptation to hypoxia is mediated by hypoxia-inducible fa...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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AME Publishing Company
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313304/ https://www.ncbi.nlm.nih.gov/pubmed/28217462 http://dx.doi.org/10.21037/tau.2017.01.12 |