Cargando…

Alcoholic Myelopathy and Nutritional Deficiency

A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower...

Descripción completa

Detalles Bibliográficos
Autores principales: Koike, Haruki, Nakamura, Tomohiko, Ikeda, Shohei, Takahashi, Mie, Kawagashira, Yuichi, Iijima, Masahiro, Katsuno, Masahisa, Sobue, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313434/
https://www.ncbi.nlm.nih.gov/pubmed/28049986
_version_ 1782508342810247168
author Koike, Haruki
Nakamura, Tomohiko
Ikeda, Shohei
Takahashi, Mie
Kawagashira, Yuichi
Iijima, Masahiro
Katsuno, Masahisa
Sobue, Gen
author_facet Koike, Haruki
Nakamura, Tomohiko
Ikeda, Shohei
Takahashi, Mie
Kawagashira, Yuichi
Iijima, Masahiro
Katsuno, Masahisa
Sobue, Gen
author_sort Koike, Haruki
collection PubMed
description A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower limbs. His cobalamin level was decreased and his serum folate level was particularly low. His plasma ammonia level was not increased. Abstinence and folic acid and cobalamin supplementation stopped the progression of his neurological deficits. This case indicates that nutritional deficiency should be monitored closely in patients with chronic alcoholism who present with myelopathy.
format Online
Article
Text
id pubmed-5313434
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-53134342017-02-28 Alcoholic Myelopathy and Nutritional Deficiency Koike, Haruki Nakamura, Tomohiko Ikeda, Shohei Takahashi, Mie Kawagashira, Yuichi Iijima, Masahiro Katsuno, Masahisa Sobue, Gen Intern Med Case Report A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower limbs. His cobalamin level was decreased and his serum folate level was particularly low. His plasma ammonia level was not increased. Abstinence and folic acid and cobalamin supplementation stopped the progression of his neurological deficits. This case indicates that nutritional deficiency should be monitored closely in patients with chronic alcoholism who present with myelopathy. The Japanese Society of Internal Medicine 2017-01-01 /pmc/articles/PMC5313434/ /pubmed/28049986 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Koike, Haruki
Nakamura, Tomohiko
Ikeda, Shohei
Takahashi, Mie
Kawagashira, Yuichi
Iijima, Masahiro
Katsuno, Masahisa
Sobue, Gen
Alcoholic Myelopathy and Nutritional Deficiency
title Alcoholic Myelopathy and Nutritional Deficiency
title_full Alcoholic Myelopathy and Nutritional Deficiency
title_fullStr Alcoholic Myelopathy and Nutritional Deficiency
title_full_unstemmed Alcoholic Myelopathy and Nutritional Deficiency
title_short Alcoholic Myelopathy and Nutritional Deficiency
title_sort alcoholic myelopathy and nutritional deficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313434/
https://www.ncbi.nlm.nih.gov/pubmed/28049986
work_keys_str_mv AT koikeharuki alcoholicmyelopathyandnutritionaldeficiency
AT nakamuratomohiko alcoholicmyelopathyandnutritionaldeficiency
AT ikedashohei alcoholicmyelopathyandnutritionaldeficiency
AT takahashimie alcoholicmyelopathyandnutritionaldeficiency
AT kawagashirayuichi alcoholicmyelopathyandnutritionaldeficiency
AT iijimamasahiro alcoholicmyelopathyandnutritionaldeficiency
AT katsunomasahisa alcoholicmyelopathyandnutritionaldeficiency
AT sobuegen alcoholicmyelopathyandnutritionaldeficiency