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Alcoholic Myelopathy and Nutritional Deficiency
A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313434/ https://www.ncbi.nlm.nih.gov/pubmed/28049986 |
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author | Koike, Haruki Nakamura, Tomohiko Ikeda, Shohei Takahashi, Mie Kawagashira, Yuichi Iijima, Masahiro Katsuno, Masahisa Sobue, Gen |
author_facet | Koike, Haruki Nakamura, Tomohiko Ikeda, Shohei Takahashi, Mie Kawagashira, Yuichi Iijima, Masahiro Katsuno, Masahisa Sobue, Gen |
author_sort | Koike, Haruki |
collection | PubMed |
description | A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower limbs. His cobalamin level was decreased and his serum folate level was particularly low. His plasma ammonia level was not increased. Abstinence and folic acid and cobalamin supplementation stopped the progression of his neurological deficits. This case indicates that nutritional deficiency should be monitored closely in patients with chronic alcoholism who present with myelopathy. |
format | Online Article Text |
id | pubmed-5313434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-53134342017-02-28 Alcoholic Myelopathy and Nutritional Deficiency Koike, Haruki Nakamura, Tomohiko Ikeda, Shohei Takahashi, Mie Kawagashira, Yuichi Iijima, Masahiro Katsuno, Masahisa Sobue, Gen Intern Med Case Report A patient with chronic alcoholism presented with myelopathy and low serum folate and cobalamin levels. A 42-year-old alcoholic man had gait disturbance for 4 months. A neurological examination revealed marked spasticity with increased deep tendon reflexes and extensor plantar responses of the lower limbs. His cobalamin level was decreased and his serum folate level was particularly low. His plasma ammonia level was not increased. Abstinence and folic acid and cobalamin supplementation stopped the progression of his neurological deficits. This case indicates that nutritional deficiency should be monitored closely in patients with chronic alcoholism who present with myelopathy. The Japanese Society of Internal Medicine 2017-01-01 /pmc/articles/PMC5313434/ /pubmed/28049986 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Koike, Haruki Nakamura, Tomohiko Ikeda, Shohei Takahashi, Mie Kawagashira, Yuichi Iijima, Masahiro Katsuno, Masahisa Sobue, Gen Alcoholic Myelopathy and Nutritional Deficiency |
title | Alcoholic Myelopathy and Nutritional Deficiency |
title_full | Alcoholic Myelopathy and Nutritional Deficiency |
title_fullStr | Alcoholic Myelopathy and Nutritional Deficiency |
title_full_unstemmed | Alcoholic Myelopathy and Nutritional Deficiency |
title_short | Alcoholic Myelopathy and Nutritional Deficiency |
title_sort | alcoholic myelopathy and nutritional deficiency |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313434/ https://www.ncbi.nlm.nih.gov/pubmed/28049986 |
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