Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature

Reactivation of hepatitis B virus (HBV) is a serious complication of immunosuppressive therapy and cytotoxic chemotherapy. The optimal duration of HBV-DNA monitoring for at-risk patients depends on the clinical features of reactivation, especially the range of potency from therapies to reactivation....

Descripción completa

Detalles Bibliográficos
Autores principales: Yamada, Toshiki, Nannya, Yasuhito, Suetsugu, Atsushi, Shimizu, Shogo, Sugihara, Junichi, Shimizu, Masahito, Seishima, Mitsuru, Tsurumi, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313436/
https://www.ncbi.nlm.nih.gov/pubmed/28049989
_version_ 1782508343235969024
author Yamada, Toshiki
Nannya, Yasuhito
Suetsugu, Atsushi
Shimizu, Shogo
Sugihara, Junichi
Shimizu, Masahito
Seishima, Mitsuru
Tsurumi, Hisashi
author_facet Yamada, Toshiki
Nannya, Yasuhito
Suetsugu, Atsushi
Shimizu, Shogo
Sugihara, Junichi
Shimizu, Masahito
Seishima, Mitsuru
Tsurumi, Hisashi
author_sort Yamada, Toshiki
collection PubMed
description Reactivation of hepatitis B virus (HBV) is a serious complication of immunosuppressive therapy and cytotoxic chemotherapy. The optimal duration of HBV-DNA monitoring for at-risk patients depends on the clinical features of reactivation, especially the range of potency from therapies to reactivation. We present a case of very late reactivation after chemotherapy for lymphoma and review previous reports of late reactivation cases. We also underscore the significance of developing an indicator for anti-HBV immunity which can be used to determine the optimal monitoring period.
format Online
Article
Text
id pubmed-5313436
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-53134362017-02-28 Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature Yamada, Toshiki Nannya, Yasuhito Suetsugu, Atsushi Shimizu, Shogo Sugihara, Junichi Shimizu, Masahito Seishima, Mitsuru Tsurumi, Hisashi Intern Med Case Report Reactivation of hepatitis B virus (HBV) is a serious complication of immunosuppressive therapy and cytotoxic chemotherapy. The optimal duration of HBV-DNA monitoring for at-risk patients depends on the clinical features of reactivation, especially the range of potency from therapies to reactivation. We present a case of very late reactivation after chemotherapy for lymphoma and review previous reports of late reactivation cases. We also underscore the significance of developing an indicator for anti-HBV immunity which can be used to determine the optimal monitoring period. The Japanese Society of Internal Medicine 2017-01-01 /pmc/articles/PMC5313436/ /pubmed/28049989 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Yamada, Toshiki
Nannya, Yasuhito
Suetsugu, Atsushi
Shimizu, Shogo
Sugihara, Junichi
Shimizu, Masahito
Seishima, Mitsuru
Tsurumi, Hisashi
Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title_full Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title_fullStr Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title_full_unstemmed Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title_short Late Reactivation of Hepatitis B Virus after Chemotherapies for Hematological Malignancies: A Case Report and Review of the Literature
title_sort late reactivation of hepatitis b virus after chemotherapies for hematological malignancies: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313436/
https://www.ncbi.nlm.nih.gov/pubmed/28049989
work_keys_str_mv AT yamadatoshiki latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT nannyayasuhito latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT suetsuguatsushi latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT shimizushogo latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT sugiharajunichi latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT shimizumasahito latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT seishimamitsuru latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature
AT tsurumihisashi latereactivationofhepatitisbvirusafterchemotherapiesforhematologicalmalignanciesacasereportandreviewoftheliterature

Ejemplares similares