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Plasma-derived parasitic microRNAs have insufficient concentrations to be used as diagnostic biomarker for detection of Onchocerca volvulus infection or treatment monitoring using LNA-based RT-qPCR
River blindness, caused by infection with the filarial nematode Onchocerca volvulus, is a neglected tropical disease affecting millions of people. There is a clear need for diagnostic tools capable of identifying infected patients, but that can also be used for monitoring disease progression and tre...
Autores principales: | Lagatie, Ole, Batsa Debrah, Linda, Debrah, Alex, Stuyver, Lieven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313568/ https://www.ncbi.nlm.nih.gov/pubmed/28111713 http://dx.doi.org/10.1007/s00436-017-5382-5 |
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