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Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection

Eye diseases caused by amoebae from the genus Acanthamoeba are usually chronic and severe, and their treatment is prolonged and not very effective. The difficulties associated with therapy have led to attempts at finding alternative treatment methods. Particularly popular is searching for cures amon...

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Autores principales: Hadaś, Edward, Derda, Monika, Cholewiński, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313585/
https://www.ncbi.nlm.nih.gov/pubmed/28124137
http://dx.doi.org/10.1007/s00436-017-5377-2
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author Hadaś, Edward
Derda, Monika
Cholewiński, Marcin
author_facet Hadaś, Edward
Derda, Monika
Cholewiński, Marcin
author_sort Hadaś, Edward
collection PubMed
description Eye diseases caused by amoebae from the genus Acanthamoeba are usually chronic and severe, and their treatment is prolonged and not very effective. The difficulties associated with therapy have led to attempts at finding alternative treatment methods. Particularly popular is searching for cures among drugs made of plants. However, no substances with total efficacy in treating Acanthamoeba keratitis have been identified. Results of our semi in vivo studies of tea tree oil simulating eyeball infection demonstrated 100% effectiveness in the case of both trophozoites and cysts of amoebae from the genus Acanthamoeba. The action of tea tree oil indicates that this is the first substance with a potential ability to quickly and effectively remove the amoebae from the eye. Tea tree oil has the ability to penetrate tissues, which allows it to destroy amoebae in both the shallow and deep layers of the cornea. The present research into the use of tea tree oil in the therapy of Acanthamoeba infection is the first study of this type in parasitology. It offers tremendous potential for effective treatment of Acanthamoeba keratitis and other diseases caused by these protozoa.
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spelling pubmed-53135852017-03-01 Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection Hadaś, Edward Derda, Monika Cholewiński, Marcin Parasitol Res Original Paper Eye diseases caused by amoebae from the genus Acanthamoeba are usually chronic and severe, and their treatment is prolonged and not very effective. The difficulties associated with therapy have led to attempts at finding alternative treatment methods. Particularly popular is searching for cures among drugs made of plants. However, no substances with total efficacy in treating Acanthamoeba keratitis have been identified. Results of our semi in vivo studies of tea tree oil simulating eyeball infection demonstrated 100% effectiveness in the case of both trophozoites and cysts of amoebae from the genus Acanthamoeba. The action of tea tree oil indicates that this is the first substance with a potential ability to quickly and effectively remove the amoebae from the eye. Tea tree oil has the ability to penetrate tissues, which allows it to destroy amoebae in both the shallow and deep layers of the cornea. The present research into the use of tea tree oil in the therapy of Acanthamoeba infection is the first study of this type in parasitology. It offers tremendous potential for effective treatment of Acanthamoeba keratitis and other diseases caused by these protozoa. Springer Berlin Heidelberg 2017-01-26 2017 /pmc/articles/PMC5313585/ /pubmed/28124137 http://dx.doi.org/10.1007/s00436-017-5377-2 Text en © The Author(s) 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Hadaś, Edward
Derda, Monika
Cholewiński, Marcin
Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title_full Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title_fullStr Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title_full_unstemmed Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title_short Evaluation of the effectiveness of tea tree oil in treatment of Acanthamoeba infection
title_sort evaluation of the effectiveness of tea tree oil in treatment of acanthamoeba infection
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313585/
https://www.ncbi.nlm.nih.gov/pubmed/28124137
http://dx.doi.org/10.1007/s00436-017-5377-2
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