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Enhancement of temozolomide stability by loading in chitosan-carboxylated polylactide-based nanoparticles
In the presented work, amphiphilic nanoparticles based on chitosan and carboxy-enriched polylactic acid have been prepared to improve the stability of the pro-drug temozolomide in physiological media by encapsulation. The carrier, with a diameter in the range of 150–180 nm, was able to accommodate u...
Autores principales: | Di Martino, Antonio, Kucharczyk, Pavel, Capakova, Zdenka, Humpolicek, Petr, Sedlarik, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313595/ https://www.ncbi.nlm.nih.gov/pubmed/28260965 http://dx.doi.org/10.1007/s11051-017-3756-3 |
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