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Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points
Chorea-Acanthocytosis (ChAc) is a rare hereditary neurological disorder characterized by abnormal movements, red blood cell pathology, and progressive neurodegeneration. Little is understood of the pathogenesis of ChAc and related disorders (collectively Neuroacanthocytosis). The Eighth Internationa...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Columbia University Libraries/Information Services
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313633/ https://www.ncbi.nlm.nih.gov/pubmed/28224046 http://dx.doi.org/10.7916/D8XD127W |
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author | Pappas, Samuel S. Bonifacino, Juan Danek, Adrian Dauer, William T. De, Mithu De Franceschi, Lucia DiPaolo, Gilbert Fuller, Robert Haucke, Volker Hermann, Andreas Kornmann, Benoit Landwehrmeyer, Bernhard Levin, Johannes Neiman, Aaron M. Rudnicki, Dobrila D. Sibon, Ody Velayos-Baeza, Antonio Vonk, Jan J. Walker, Ruth H. Weisman, Lois S. Albin, Roger L. |
author_facet | Pappas, Samuel S. Bonifacino, Juan Danek, Adrian Dauer, William T. De, Mithu De Franceschi, Lucia DiPaolo, Gilbert Fuller, Robert Haucke, Volker Hermann, Andreas Kornmann, Benoit Landwehrmeyer, Bernhard Levin, Johannes Neiman, Aaron M. Rudnicki, Dobrila D. Sibon, Ody Velayos-Baeza, Antonio Vonk, Jan J. Walker, Ruth H. Weisman, Lois S. Albin, Roger L. |
author_sort | Pappas, Samuel S. |
collection | PubMed |
description | Chorea-Acanthocytosis (ChAc) is a rare hereditary neurological disorder characterized by abnormal movements, red blood cell pathology, and progressive neurodegeneration. Little is understood of the pathogenesis of ChAc and related disorders (collectively Neuroacanthocytosis). The Eighth International Chorea-Acanthocytosis Symposium was held in May 2016 in Ann Arbor, MI, USA, and focused on molecular mechanisms driving ChAc pathophysiology. Accompanying the meeting, members of the neuroacanthocytosis research community and other invited scientists met in a workshop to discuss the current understanding and next steps needed to better understand ChAc pathogenesis. These discussions identified several broad and critical needs for advancing ChAc research and patient care, and led to the definition of 18 specific action points related to functional and molecular studies, animal models, and clinical research. These action points, described below, represent tractable research goals to pursue for the next several years. |
format | Online Article Text |
id | pubmed-5313633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Columbia University Libraries/Information Services |
record_format | MEDLINE/PubMed |
spelling | pubmed-53136332017-02-21 Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points Pappas, Samuel S. Bonifacino, Juan Danek, Adrian Dauer, William T. De, Mithu De Franceschi, Lucia DiPaolo, Gilbert Fuller, Robert Haucke, Volker Hermann, Andreas Kornmann, Benoit Landwehrmeyer, Bernhard Levin, Johannes Neiman, Aaron M. Rudnicki, Dobrila D. Sibon, Ody Velayos-Baeza, Antonio Vonk, Jan J. Walker, Ruth H. Weisman, Lois S. Albin, Roger L. Tremor Other Hyperkinet Mov (N Y) Conference Proceedings Chorea-Acanthocytosis (ChAc) is a rare hereditary neurological disorder characterized by abnormal movements, red blood cell pathology, and progressive neurodegeneration. Little is understood of the pathogenesis of ChAc and related disorders (collectively Neuroacanthocytosis). The Eighth International Chorea-Acanthocytosis Symposium was held in May 2016 in Ann Arbor, MI, USA, and focused on molecular mechanisms driving ChAc pathophysiology. Accompanying the meeting, members of the neuroacanthocytosis research community and other invited scientists met in a workshop to discuss the current understanding and next steps needed to better understand ChAc pathogenesis. These discussions identified several broad and critical needs for advancing ChAc research and patient care, and led to the definition of 18 specific action points related to functional and molecular studies, animal models, and clinical research. These action points, described below, represent tractable research goals to pursue for the next several years. Columbia University Libraries/Information Services 2017-02-15 /pmc/articles/PMC5313633/ /pubmed/28224046 http://dx.doi.org/10.7916/D8XD127W Text en © 2017 Pappas et al. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution–Noncommerical–No Derivatives License, which permits the user to copy, distribute, and transmit the work provided that the original author and source are credited; that no commercial use is made of the work; and that the work is not altered or transformed. |
spellingShingle | Conference Proceedings Pappas, Samuel S. Bonifacino, Juan Danek, Adrian Dauer, William T. De, Mithu De Franceschi, Lucia DiPaolo, Gilbert Fuller, Robert Haucke, Volker Hermann, Andreas Kornmann, Benoit Landwehrmeyer, Bernhard Levin, Johannes Neiman, Aaron M. Rudnicki, Dobrila D. Sibon, Ody Velayos-Baeza, Antonio Vonk, Jan J. Walker, Ruth H. Weisman, Lois S. Albin, Roger L. Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title | Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title_full | Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title_fullStr | Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title_full_unstemmed | Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title_short | Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points |
title_sort | eighth international chorea–acanthocytosis symposium: summary of workshop discussion and action points |
topic | Conference Proceedings |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313633/ https://www.ncbi.nlm.nih.gov/pubmed/28224046 http://dx.doi.org/10.7916/D8XD127W |
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