Nonpromoter methylation of the CDKN2A gene with active transcription is associated with improved locoregional control in laryngeal squamous cell carcinoma

We previously reported a novel association between CDKN2A nonpromoter methylation and transcription (ARF/INK4a) in human papillomavirus associated oropharyngeal tumors. In this study we assessed whether nonpromoter CDKN2A methylation in laryngeal squamous cell carcinomas (LXSCC) conferred a similar...

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Detalles Bibliográficos
Autores principales: Ben‐Dayan, Miriam M., Ow, Thomas J., Belbin, Thomas J., Wetzler, Joshua, Smith, Richard V., Childs, Geoffrey, Diergaarde, Brenda, Hayes, D. Neil, Grandis, Jennifer R., Prystowsky, Michael B., Schlecht, Nicolas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313649/
https://www.ncbi.nlm.nih.gov/pubmed/28102032
http://dx.doi.org/10.1002/cam4.961

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