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Dissection of major depressive disorder using polygenic risk scores for schizophrenia in two independent cohorts
Major depressive disorder (MDD) is known for its substantial clinical and suspected causal heterogeneity. It is characterized by low mood, psychomotor slowing and increased levels of the personality trait neuroticism; factors also associated with schizophrenia (SCZ). It is possible that some cases o...
Autores principales: | Whalley, H C, Adams, M J, Hall, L S, Clarke, T-K, Fernandez-Pujals, A M, Gibson, J, Wigmore, E, Hafferty, J, Hagenaars, S P, Davies, G, Campbell, A, Hayward, C, Lawrie, S M, Porteous, D J, Deary, I J, McIntosh, A M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314119/ https://www.ncbi.nlm.nih.gov/pubmed/27801894 http://dx.doi.org/10.1038/tp.2016.207 |
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