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Transient Cannabinoid Receptor 2 Blockade during Immunization Heightens Intensity and Breadth of Antigen-specific Antibody Responses in Young and Aged mice
The hallmark of vaccines is their ability to prevent the spread of infectious pathogens and thereby serve as invaluable public health tool. Despite their medical relevance, there is a gap in our understanding of the physiological factors that mediate innate and adaptive immune response to vaccines....
Autores principales: | Dotsey, Emmanuel, Ushach, Irina, Pone, Egest, Nakajima, Rie, Jasinskas, Algis, Argueta, Donovan A., Dillon, Andrea, DiPatrizio, Nicholas, Davies, Huw, Zlotnik, Albert, Crompton, Peter D., Felgner, Philip L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314369/ https://www.ncbi.nlm.nih.gov/pubmed/28209996 http://dx.doi.org/10.1038/srep42584 |
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