Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors

Oncogene amplification confers a growth advantage to tumor cells for clonal expansion. There are several, recurrently amplified oncogenes throughout the human genome. However, it remains unclear whether this recurrent amplification is solely a manifestation of increased fitness resulting from random...

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Detalles Bibliográficos
Autores principales: Marotta, Michael, Onodera, Taku, Johnson, Jeffrey, Budd, G. Thomas, Watanabe, Takaaki, Cui, Xiaojiang, Giuliano, Armando E., Niida, Atsushi, Tanaka, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314454/
https://www.ncbi.nlm.nih.gov/pubmed/28211519
http://dx.doi.org/10.1038/srep41921

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