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RNF40 regulates gene expression in an epigenetic context-dependent manner
BACKGROUND: Monoubiquitination of H2B (H2Bub1) is a largely enigmatic histone modification that has been linked to transcriptional elongation. Because of this association, it has been commonly assumed that H2Bub1 is an exclusively positively acting histone modification and that increased H2Bub1 occu...
Autores principales: | Xie, Wanhua, Nagarajan, Sankari, Baumgart, Simon J., Kosinsky, Robyn Laura, Najafova, Zeynab, Kari, Vijayalakshmi, Hennion, Magali, Indenbirken, Daniela, Bonn, Stefan, Grundhoff, Adam, Wegwitz, Florian, Mansouri, Ahmed, Johnsen, Steven A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314486/ https://www.ncbi.nlm.nih.gov/pubmed/28209164 http://dx.doi.org/10.1186/s13059-017-1159-5 |
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