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Epigenetic and genetic deregulation in cancer target distinct signaling pathway domains
Cancer is characterized by both genetic and epigenetic alterations. While cancer driver mutations and copy-number alterations have been studied at a systems-level, relatively little is known about the systems-level patterns exhibited by their epigenetic counterparts. Here we perform a pan-cancer wid...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314760/ https://www.ncbi.nlm.nih.gov/pubmed/27899617 http://dx.doi.org/10.1093/nar/gkw1100 |