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Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament
Homologous recombination (HR) is a crucial pathway for double-stranded DNA break (DSB) repair. During the early stages of HR, the newly generated DSB ends are processed to yield long single-stranded DNA (ssDNA) overhangs, which are quickly bound by replication protein A (RPA). RPA is then replaced b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314761/ https://www.ncbi.nlm.nih.gov/pubmed/27903895 http://dx.doi.org/10.1093/nar/gkw1125 |