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The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome

The eukaryotic RNA exosome is an essential, multi-subunit complex that catalyzes RNA turnover, maturation, and quality control processes. Its non-catalytic donut-shaped core includes 9 subunits that associate with the 3′ to 5′ exoribonucleases Rrp6, and Rrp44/Dis3, a subunit that also catalyzes endo...

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Detalles Bibliográficos
Autores principales:	Wasmuth, Elizabeth V., Lima, Christopher D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314766/ https://www.ncbi.nlm.nih.gov/pubmed/27899565 http://dx.doi.org/10.1093/nar/gkw1152

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