Structural insights into dynamics of RecU–HJ complex formation elucidates key role of NTR and stalk region toward formation of reactive state

Holliday junction (HJ) resolving enzyme RecU is involved in DNA repair and recombination. We have determined the crystal structure of inactive mutant (D88N) of RecU from Bacillus subtilis in complex with a 12 base palindromic DNA fragment at a resolution of 3.2 Å. This structure shows the stalk regi...

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Detalles Bibliográficos
Autores principales: Khavnekar, Sagar, Dantu, Sarath Chandra, Sedelnikova, Svetlana, Ayora, Sylvia, Rafferty, John, Kale, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314769/
https://www.ncbi.nlm.nih.gov/pubmed/27903910
http://dx.doi.org/10.1093/nar/gkw1165

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