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Ribonuclease selection for ribosome profiling

Ribosome profiling has emerged as a powerful method to assess global gene translation, but methodological and analytical challenges often lead to inconsistencies across labs and model organisms. A critical issue in ribosome profiling is nuclease treatment of ribosome–mRNA complexes, as it is importa...

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Detalles Bibliográficos
Autores principales: Gerashchenko, Maxim V., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314788/
https://www.ncbi.nlm.nih.gov/pubmed/27638886
http://dx.doi.org/10.1093/nar/gkw822

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