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Ubiquitylation-dependent regulation of NEIL1 by Mule and TRIM26 is required for the cellular DNA damage response

Endonuclease VIII-like protein 1 (NEIL1) is a DNA glycosylase involved in initiating the base excision repair pathway, the major cellular mechanism for repairing DNA base damage. Here, we have purified the major E3 ubiquitin ligases from human cells responsible for regulation of NEIL1 by ubiquitylat...

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Detalles Bibliográficos
Autores principales:	Edmonds, Matthew J., Carter, Rachel J., Nickson, Catherine M., Williams, Sarah C., Parsons, Jason L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314803/ https://www.ncbi.nlm.nih.gov/pubmed/27924031 http://dx.doi.org/10.1093/nar/gkw959

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