Formation of covalent di-tyrosine dimers in recombinant α-synuclein

Parkinson's disease is associated with fibril deposition in the diseased brain. Misfolding events of the intrinsically disordered synaptic protein α-synuclein are suggested to lead to the formation of transient oligomeric and cytotoxic species. The etiology of Parkinson's disease is furthe...

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Detalles Bibliográficos
Autores principales: van Maarschalkerweerd, A, Pedersen, MN, Peterson, H, Nilsson, M, Nguyen, TTT, Skamris, T, Rand, K, Vetri, V, Langkilde, AE, Vestergaard, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314896/
https://www.ncbi.nlm.nih.gov/pubmed/28232892
http://dx.doi.org/10.1080/21690707.2015.1071302

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