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The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation

Ultra-pulsed fractional CO(2) laser is an efficient, precise, and safe therapeutic intervention for skin refreshing, although accompanied with prolonged edema and erythema. In recent years, autologous platelet-rich plasma (PRP) has been proven to promote wound and soft tissue healing and collagen re...

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Autores principales: Hui, Qiang, Chang, Peng, Guo, Bingyu, Zhang, Yu, Tao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314998/
https://www.ncbi.nlm.nih.gov/pubmed/27222038
http://dx.doi.org/10.1089/rej.2016.1823
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author Hui, Qiang
Chang, Peng
Guo, Bingyu
Zhang, Yu
Tao, Kai
author_facet Hui, Qiang
Chang, Peng
Guo, Bingyu
Zhang, Yu
Tao, Kai
author_sort Hui, Qiang
collection PubMed
description Ultra-pulsed fractional CO(2) laser is an efficient, precise, and safe therapeutic intervention for skin refreshing, although accompanied with prolonged edema and erythema. In recent years, autologous platelet-rich plasma (PRP) has been proven to promote wound and soft tissue healing and collagen regeneration. To investigate whether the combination of PRP and ultra-pulsed fractional CO(2) laser had a synergistic effect on therapy for facial rejuvenation. Totally, 13 facial aging females were treated with ultra-pulsed fractional CO(2) laser. One side of the face was randomly selected as experimental group and injected with PRP, the other side acted as the control group and was injected with physiological saline at the same dose. Comprehensive assessment of clinical efficacy was performed by satisfaction scores, dermatologists' double-blind evaluation and the VISIA skin analysis system. After treatment for 3 months, subjective scores of facial wrinkles, skin texture, and skin elasticity were higher than that in the control group. Similarly, improvement of skin wrinkles, texture, and tightness in the experimental group was better compared with the control group. Additionally, the total duration of erythema, edema, and crusting was decreased, in the experimental group compared with the control group. PRP combined with ultra-pulsed fractional CO(2) laser had a synergistic effect on facial rejuvenation, shortening duration of side effects, and promoting better therapeutic effect.
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spelling pubmed-53149982017-03-06 The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation Hui, Qiang Chang, Peng Guo, Bingyu Zhang, Yu Tao, Kai Rejuvenation Res Original Articles Ultra-pulsed fractional CO(2) laser is an efficient, precise, and safe therapeutic intervention for skin refreshing, although accompanied with prolonged edema and erythema. In recent years, autologous platelet-rich plasma (PRP) has been proven to promote wound and soft tissue healing and collagen regeneration. To investigate whether the combination of PRP and ultra-pulsed fractional CO(2) laser had a synergistic effect on therapy for facial rejuvenation. Totally, 13 facial aging females were treated with ultra-pulsed fractional CO(2) laser. One side of the face was randomly selected as experimental group and injected with PRP, the other side acted as the control group and was injected with physiological saline at the same dose. Comprehensive assessment of clinical efficacy was performed by satisfaction scores, dermatologists' double-blind evaluation and the VISIA skin analysis system. After treatment for 3 months, subjective scores of facial wrinkles, skin texture, and skin elasticity were higher than that in the control group. Similarly, improvement of skin wrinkles, texture, and tightness in the experimental group was better compared with the control group. Additionally, the total duration of erythema, edema, and crusting was decreased, in the experimental group compared with the control group. PRP combined with ultra-pulsed fractional CO(2) laser had a synergistic effect on facial rejuvenation, shortening duration of side effects, and promoting better therapeutic effect. Mary Ann Liebert, Inc. 2017-02-01 2017-02-01 /pmc/articles/PMC5314998/ /pubmed/27222038 http://dx.doi.org/10.1089/rej.2016.1823 Text en © Qiang Hui et al., 2017; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons Attribution Noncommercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Original Articles
Hui, Qiang
Chang, Peng
Guo, Bingyu
Zhang, Yu
Tao, Kai
The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title_full The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title_fullStr The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title_full_unstemmed The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title_short The Clinical Efficacy of Autologous Platelet-Rich Plasma Combined with Ultra-Pulsed Fractional CO(2) Laser Therapy for Facial Rejuvenation
title_sort clinical efficacy of autologous platelet-rich plasma combined with ultra-pulsed fractional co(2) laser therapy for facial rejuvenation
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314998/
https://www.ncbi.nlm.nih.gov/pubmed/27222038
http://dx.doi.org/10.1089/rej.2016.1823
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