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Asymmetric synthesis of cyclopentanes bearing four contiguous stereocenters via an NHC-catalyzed Michael/Michael/esterification domino reaction

An NHC-catalyzed Michael/Michael/esterification domino reaction via homoenolate/enolate intermediates for the asymmetric synthesis of tetrasubstituted cyclopentanes bearing four contiguous stereocenters is described. A variety of α,β-unsaturated aldehydes and 2-nitroallylic acetates react well with...

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Detalles Bibliográficos
Autores principales:	Shu, Tao, Ni, Qijian, Song, Xiaoxiao, Zhao, Kun, Wu, Tianyu, Puttreddy, Rakesh, Rissanen, Kari, Enders, Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2016
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315016/ https://www.ncbi.nlm.nih.gov/pubmed/26750327 http://dx.doi.org/10.1039/c5cc09581f

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