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Conformational diversity and enantioconvergence in potato epoxide hydrolase 1
Potato epoxide hydrolase 1 (StEH1) is a biocatalytically important enzyme that exhibits rich enantio- and regioselectivity in the hydrolysis of chiral epoxide substrates. In particular, StEH1 has been demonstrated to enantioconvergently hydrolyze racemic mixes of styrene oxide (SO) to yield (R)-1-ph...
Autores principales: | Bauer, P., Carlsson, Å. Janfalk, Amrein, B. A., Dobritzsch, D., Widersten, M., Kamerlin, S. C. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315018/ https://www.ncbi.nlm.nih.gov/pubmed/27049844 http://dx.doi.org/10.1039/c6ob00060f |
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