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Repeated short climatic change affects the epidermal differentiation program and leads to matrix remodeling in a human organotypic skin model

Human skin is subject to frequent changes in ambient temperature and humidity and needs to cope with these environmental modifications. To decipher the molecular response of human skin to repeated climatic change, a versatile model of skin equivalent subject to “hot–wet” (40°C, 80% relative humidity...

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Detalles Bibliográficos
Autores principales: Boutrand, Laetitia-Barbollat, Thépot, Amélie, Muther, Charlotte, Boher, Aurélie, Robic, Julie, Guéré, Christelle, Vié, Katell, Damour, Odile, Lamartine, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315211/
https://www.ncbi.nlm.nih.gov/pubmed/28243135
http://dx.doi.org/10.2147/CCID.S120800