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Repeated short climatic change affects the epidermal differentiation program and leads to matrix remodeling in a human organotypic skin model
Human skin is subject to frequent changes in ambient temperature and humidity and needs to cope with these environmental modifications. To decipher the molecular response of human skin to repeated climatic change, a versatile model of skin equivalent subject to “hot–wet” (40°C, 80% relative humidity...
Autores principales: | Boutrand, Laetitia-Barbollat, Thépot, Amélie, Muther, Charlotte, Boher, Aurélie, Robic, Julie, Guéré, Christelle, Vié, Katell, Damour, Odile, Lamartine, Jérôme |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315211/ https://www.ncbi.nlm.nih.gov/pubmed/28243135 http://dx.doi.org/10.2147/CCID.S120800 |
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