Heterogeneous dimer peptide-conjugated polylysine dendrimer-Fe(3)O(4) composite as a novel nanoscale molecular probe for early diagnosis and therapy in hepatocellular carcinoma

A novel nanoscale molecular probe is formulated in order to reduce toxicity and side effects of antitumor drug doxorubicin (DOX) in normal tissues and to enhance the detection sensitivity during early imaging diagnosis. The mechanism involves a specific targeting of Arg-Gly-Asp peptide (RGD)-GX1 het...

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Detalles Bibliográficos
Autores principales: Shen, Jian-Min, Li, Xin-Xin, Fan, Lin-Lan, Zhou, Xing, Han, Ji-Min, Jia, Ming-Kang, Wu, Liang-Fan, Zhang, Xiao-Xue, Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315215/
https://www.ncbi.nlm.nih.gov/pubmed/28243083
http://dx.doi.org/10.2147/IJN.S126887

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