SplitAx: A novel method to assess the function of engineered nucleases

Engineered nucleases have been used to generate knockout or reporter cell lines and a range of animal models for human disease. These new technologies also hold great promise for therapeutic genome editing. Current methods to evaluate the activity of these nucleases are time consuming, require exten...

Descripción completa

Detalles Bibliográficos
Autores principales: Axton, Richard A., Haideri, Sharmin S., Lopez-Yrigoyen, Martha, Taylor, Helen A., Forrester, Lesley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315338/
https://www.ncbi.nlm.nih.gov/pubmed/28212417
http://dx.doi.org/10.1371/journal.pone.0171698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315338/
https://www.ncbi.nlm.nih.gov/pubmed/28212417
http://dx.doi.org/10.1371/journal.pone.0171698

Ejemplares similares