Bay11-7082 attenuates neuropathic pain via inhibition of nuclear factor-kappa B and nucleotide-binding domain-like receptor protein 3 inflammasome activation in dorsal root ganglions in a rat model of lumbar disc herniation

Lumbar disc herniation (LDH) is an important cause of radiculopathy, but the underlying mechanisms are incompletely understood. Many studies suggested that local inflammation, rather than mechanical compression, results in radiculopathy induced by LDH. On the molecular and cellular level, nuclear fa...

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Detalles Bibliográficos
Autores principales: Zhang, Ailiang, Wang, Kun, Ding, Lianghua, Bao, Xinnan, Wang, Xuan, Qiu, Xubin, Liu, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315342/
https://www.ncbi.nlm.nih.gov/pubmed/28243141
http://dx.doi.org/10.2147/JPR.S119820

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