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AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway
Absent in melanoma 2 (AIM2) plays an important role in innate immunity as a DNA sensor in the cytoplasm by triggering the assembly of an AIM2 inflammasome that results in caspase-1-mediated inflammatory responses and cell death. In recent years, studies have indicated that AIM2 can suppress cancer c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315344/ https://www.ncbi.nlm.nih.gov/pubmed/28243117 http://dx.doi.org/10.2147/OTT.S125039 |