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AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway

Absent in melanoma 2 (AIM2) plays an important role in innate immunity as a DNA sensor in the cytoplasm by triggering the assembly of an AIM2 inflammasome that results in caspase-1-mediated inflammatory responses and cell death. In recent years, studies have indicated that AIM2 can suppress cancer c...

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Detalles Bibliográficos
Autores principales:	Chen, Jianjun, Wang, Zhenjun, Yu, Sanshui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315344/ https://www.ncbi.nlm.nih.gov/pubmed/28243117 http://dx.doi.org/10.2147/OTT.S125039

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