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Lack of mycothiol and ergothioneine induces different protective mechanisms in Mycobacterium smegmatis

Mycobacterium smegmatis contains the low molecular weight thiols, mycothiol (MSH) and ergothioneine (ESH). Examination of transposon mutants disrupted in mshC and egtA, involved in the biosynthesis of MSH and ESH respectively, demonstrated that both mutants were sensitive to oxidative, alkylating, a...

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Detalles Bibliográficos
Autores principales: Singh, Arishma Rajkarnikar, Strankman, Andrew, Orkusyan, Ruzan, Purwantini, Endang, Rawat, Mamta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315357/
https://www.ncbi.nlm.nih.gov/pubmed/28220152
http://dx.doi.org/10.1016/j.bbrep.2016.08.006

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