A novel hemagglutinin protein produced in bacteria protects chickens against H5N1 highly pathogenic avian influenza viruses by inducing H5 subtype-specific neutralizing antibodies

The highly pathogenic (HP) H5N1 avian influenza viruses (AIVs) cause a mortality rate of up to 100% in infected chickens and pose a permanent pandemic threat. Attempts to obtain effective vaccines against H5N1 HPAIVs have focused on hemagglutinin (HA), an immunodominant viral antigen capable of elic...

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Detalles Bibliográficos
Autores principales: Sączyńska, Violetta, Romanik, Agnieszka, Florys, Katarzyna, Cecuda-Adamczewska, Violetta, Kęsik-Brodacka, Małgorzata, Śmietanka, Krzysztof, Olszewska, Monika, Domańska-Blicharz, Katarzyna, Minta, Zenon, Szewczyk, Bogusław, Płucienniczak, Grażyna, Płucienniczak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315377/
https://www.ncbi.nlm.nih.gov/pubmed/28212428
http://dx.doi.org/10.1371/journal.pone.0172008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315377/
https://www.ncbi.nlm.nih.gov/pubmed/28212428
http://dx.doi.org/10.1371/journal.pone.0172008

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