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Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence

B-cell receptor (BCR)-mediated signaling plays an important role in the pathogenesis of a subset of diffuse large B-cell lymphoma (DLBCL), and novel agents targeting this pathway are now in clinical use. We have previously identified a signature of active BCR signaling on formalin-fixed paraffin-emb...

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Detalles Bibliográficos
Autores principales: Bogusz, Agata M., Kovach, Alexandra E., Le, Long P., Feng, Derek, Baxter, Richard H. G., Sohani, Aliyah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315400/
https://www.ncbi.nlm.nih.gov/pubmed/28212447
http://dx.doi.org/10.1371/journal.pone.0172364