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Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence
B-cell receptor (BCR)-mediated signaling plays an important role in the pathogenesis of a subset of diffuse large B-cell lymphoma (DLBCL), and novel agents targeting this pathway are now in clinical use. We have previously identified a signature of active BCR signaling on formalin-fixed paraffin-emb...
Autores principales: | Bogusz, Agata M., Kovach, Alexandra E., Le, Long P., Feng, Derek, Baxter, Richard H. G., Sohani, Aliyah R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315400/ https://www.ncbi.nlm.nih.gov/pubmed/28212447 http://dx.doi.org/10.1371/journal.pone.0172364 |
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