Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases

OBJECTIVES: The efficacy of a partial agonist for the dopamine D(2) receptor, aripiprazole, for catatonia in schizophrenia has been reported. METHODS: We report distinct clinical courses in challenging aripiprazole to treat residual mutism after severe catatonic symptoms improved. RESULTS: In the fi...

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Detalles Bibliográficos
Autores principales: Muneoka, Katsumasa, Kanahara, Nobuhisa, Kimura, Shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315413/
https://www.ncbi.nlm.nih.gov/pubmed/28255444
http://dx.doi.org/10.1177/2050313X17692936
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author Muneoka, Katsumasa
Kanahara, Nobuhisa
Kimura, Shou
author_facet Muneoka, Katsumasa
Kanahara, Nobuhisa
Kimura, Shou
author_sort Muneoka, Katsumasa
collection PubMed
description OBJECTIVES: The efficacy of a partial agonist for the dopamine D(2) receptor, aripiprazole, for catatonia in schizophrenia has been reported. METHODS: We report distinct clinical courses in challenging aripiprazole to treat residual mutism after severe catatonic symptoms improved. RESULTS: In the first case, mutism was successfully treated when the patient was switched from olanzapine to aripiprazole. In contract, switching to aripiprazole from risperidone aggravated auditory hallucinations in the second case. CONCLUSIONS: We will discuss the benefits and risks of using aripiprazole for the treatment of catatonic schizophrenia and the possibility of dopamine supersensitivity psychosis.
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spelling pubmed-53154132017-03-02 Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases Muneoka, Katsumasa Kanahara, Nobuhisa Kimura, Shou SAGE Open Med Case Rep Case Report OBJECTIVES: The efficacy of a partial agonist for the dopamine D(2) receptor, aripiprazole, for catatonia in schizophrenia has been reported. METHODS: We report distinct clinical courses in challenging aripiprazole to treat residual mutism after severe catatonic symptoms improved. RESULTS: In the first case, mutism was successfully treated when the patient was switched from olanzapine to aripiprazole. In contract, switching to aripiprazole from risperidone aggravated auditory hallucinations in the second case. CONCLUSIONS: We will discuss the benefits and risks of using aripiprazole for the treatment of catatonic schizophrenia and the possibility of dopamine supersensitivity psychosis. SAGE Publications 2017-02-08 /pmc/articles/PMC5315413/ /pubmed/28255444 http://dx.doi.org/10.1177/2050313X17692936 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Muneoka, Katsumasa
Kanahara, Nobuhisa
Kimura, Shou
Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title_full Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title_fullStr Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title_full_unstemmed Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title_short Switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
title_sort switching to aripiprazole for the treatment of residual mutism resulted in distinct clinical courses in two catatonic schizophrenia cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315413/
https://www.ncbi.nlm.nih.gov/pubmed/28255444
http://dx.doi.org/10.1177/2050313X17692936
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AT kimurashou switchingtoaripiprazoleforthetreatmentofresidualmutismresultedindistinctclinicalcoursesintwocatatonicschizophreniacases

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