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The p53 isoform delta133p53ß regulates cancer cell apoptosis in a RhoB-dependent manner
The TP53 gene plays essential roles in cancer. Conventionally, wild type (WT) p53 is thought to prevent cancer development and metastasis formation, while mutant p53 has transforming abilities. However, clinical studies failed to establish p53 mutation status as an unequivocal predictive or prognost...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315499/ https://www.ncbi.nlm.nih.gov/pubmed/28212429 http://dx.doi.org/10.1371/journal.pone.0172125 |