RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer's disease: genome-wide transcriptomic profiling and bioinformatics data mining

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Alzheimer's disease (AD) is the most frequent cause of dementia. Misfolded protein pathological hallmarks of AD are brain deposits of amyloid-β (Aβ) plaques and phosphorylated tau neurofibrillary tangles. However, doubts about the role of Aβ in AD pathology have been raised as Aβ is a common co...

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Detalles Bibliográficos
Autores principales: Hadar, A, Milanesi, E, Squassina, A, Niola, P, Chillotti, C, Pasmanik-Chor, M, Yaron, O, Martásek, P, Rehavi, M, Weissglas-Volkov, D, Shomron, N, Gozes, I, Gurwitz, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315547/
https://www.ncbi.nlm.nih.gov/pubmed/27701409
http://dx.doi.org/10.1038/tp.2016.179
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