A human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice

Patients with Alzheimer's disease (AD), a common dementia among the aging population, often also suffer from depression. This comorbidity is poorly understood. Although most forms of AD are not genetically inherited, we have identified a new human mutation in the carboxypeptidase E (CPE)/neurot...

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Detalles Bibliográficos
Autores principales: Cheng, Y, Cawley, N X, Yanik, T, Murthy, S R K, Liu, C, Kasikci, F, Abebe, D, Loh, Y P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315563/
https://www.ncbi.nlm.nih.gov/pubmed/27922637
http://dx.doi.org/10.1038/tp.2016.237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315563/
https://www.ncbi.nlm.nih.gov/pubmed/27922637
http://dx.doi.org/10.1038/tp.2016.237

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