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c-Met expression and activity in urogenital cancers – novel aspects of signal transduction and medical implications

C-Met is a receptor tyrosine kinase with multiple functions throughout embryonic development, organogenesis and wound healing and is expressed in various epithelia. The ligand of c-Met is Hepatocyte Growth Factor (HGF) which is secreted among others by mesenchymal stroma/stem (MSC) cells. Physiologi...

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Detalles Bibliográficos
Autores principales:	Hass, Ralf, Jennek, Susanne, Yang, Yuanyuan, Friedrich, Karlheinz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316205/ https://www.ncbi.nlm.nih.gov/pubmed/28212658 http://dx.doi.org/10.1186/s12964-017-0165-2

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