Cargando…

Anti-malarial effect of novel chloroquine derivatives as agents for the treatment of malaria

BACKGROUND: The widespread emergence of anti-malarial drug resistance has necessitated the discovery of novel anti-malarial drug candidates. In this study, chloroquine derivatives were evaluated for the improved anti-malarial activity. RESULTS: Novel two derivatives (SKM13 and SKM14) were synthesize...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yeo, Seon-Ju, Liu, Dong-Xu, Kim, Hak Sung, Park, Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316213/ https://www.ncbi.nlm.nih.gov/pubmed/28212631 http://dx.doi.org/10.1186/s12936-017-1725-z

Ejemplares similares

Metal-chloroquine derivatives as possible anti-malarial drugs: evaluation of anti-malarial activity and mode of action
por: Navarro, Maribel, et al.
Publicado: (2014)

Active case detection, treatment of falciparum malaria with combined chloroquine and sulphadoxine/pyrimethamine and vivax malaria with chloroquine and molecular markers of anti-malarial resistance in the Republic of Vanuatu
por: Kinzer, Michael H, et al.
Publicado: (2010)

Anti-malarial activity of HCl salt of SKM13 (SKM13-2HCl)
por: Trinh, Thuy-Tien Thi, et al.
Publicado: (2022)

Efficacy and Safety of Anti-malarial Drugs (Chloroquine and Hydroxy-Chloroquine) in Treatment of COVID-19 Infection: A Systematic Review and Meta-Analysis
por: Das, Rashmi Ranjan, et al.
Publicado: (2020)

In Vivo Anti-Malarial Activity of Heracleum persicum Fruit Extract, in Combination with Chloroquine against Chloroquine–Sensitive Strain of Plasmodium berghei
por: MAZHARI, Nahideh, et al.
Publicado: (2018)

In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in combination with chloroquine
por: Sahu, Rajnish, et al.
Publicado: (2014)

Novel pantothenate derivatives for anti-malarial chemotherapy
por: Pett, Helmi E, et al.
Publicado: (2015)

Injectable anti-malarials revisited: discovery and development of new agents to protect against malaria
por: Macintyre, Fiona, et al.
Publicado: (2018)

Discovery of a selective, safe and novel anti-malarial compound with activity against chloroquine resistant strain of Plasmodium falciparum
por: Agarwal, Ankita, et al.
Publicado: (2015)

Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations
por: Khalil, Insaf F, et al.
Publicado: (2011)

The role of anti-malarial drugs in eliminating malaria
por: White, Nicholas J
Publicado: (2008)

Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis
por: Shiryaev, Sergey A., et al.
Publicado: (2017)

Anti-malarial drugs and the prevention of malaria in the population of malaria endemic areas
por: Greenwood, Brian
Publicado: (2010)

Systematic review and meta-analysis of the safety of chloroquine and hydroxychloroquine from randomized controlled trials on malarial and non-malarial conditions
por: Souza Botelho, Mayra, et al.
Publicado: (2021)

The anti-malarial chloroquine overcomes Primary resistance and restores sensitivity to Trastuzumab in HER2-positive breast cancer
por: Cufí, Sílvia, et al.
Publicado: (2013)

Malaria and Malarial Diseases
Publicado: (1884)

Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections
por: Vergote, Valentijn, et al.
Publicado: (2021)

Evaluation of the effect of supervised anti-malarial treatment on recurrences of Plasmodium vivax malaria
por: Dinelly, Kelry Mazurega Oliveira, et al.
Publicado: (2021)

Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19
por: Lei, Zi-Ning, et al.
Publicado: (2020)

A new anti-malarial drug against murine malaria
por: Zamani, Zahra, et al.
Publicado: (2011)

The effect of malaria and anti-malarial drugs on skeletal and cardiac muscles
por: Marrelli, Mauro Toledo, et al.
Publicado: (2016)

Anti‐malarial drug effects on parasite dynamics in vivax malaria
por: White, Nicholas J.
Publicado: (2021)

Anti-malarial plants in Ethiopia and their activities on drug-resistant malaria
por: Sema, Yimeslal Atnafu, et al.
Publicado: (2022)

Anti-malarial prescriptions in three health care facilities after the emergence of chloroquine resistance in Niakhar, Senegal (1992–2004)
por: Munier, Aline, et al.
Publicado: (2009)

Effective treatment with a tetrandrine/chloroquine combination for chloroquine-resistant falciparum malaria in Aotus monkeys
por: Ye, Zuguang, et al.
Publicado: (2013)

Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy
por: Chico, R Matthew, et al.
Publicado: (2008)

Efficacy of Chloroquine for the Treatment of Vivax malaria in Northwest Ethiopia
por: Beyene, Habtamu Bedimo, et al.
Publicado: (2016)

A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents
por: Bahamontes-Rosa, Noemí, et al.
Publicado: (2016)

Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
por: Achan, Jane, et al.
Publicado: (2011)

A Novel RP-HPLC-DAD Method Development for Anti-Malarial and COVID-19 Hydroxy Chloroquine Sulfate Tablets and Profiling of In-Vitro Dissolution in Multimedia.
por: DONGALA, THIRUPATHI, et al.
Publicado: (2020)

Monitoring of efficacy and safety of artemisinin-based anti-malarials for treatment of uncomplicated malaria: a review of evidence of implementation of anti-malarial therapeutic efficacy trials in Tanzania
por: Shayo, Alex, et al.
Publicado: (2015)

Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges
por: Dahal, Prabin, et al.
Publicado: (2017)

Pharmacopeial quality of artemether–lumefantrine anti-malarial agents in Uganda
por: Ocan, Moses, et al.
Publicado: (2023)

Anti-malarial drug, artemisinin and its derivatives for the treatment of respiratory diseases
por: Cheong, Dorothy H.J., et al.
Publicado: (2020)

Anti-malarial activity of geldanamycin derivatives in mice infected with Plasmodium yoelii
por: Mout, Rubul, et al.
Publicado: (2012)

Transmission dynamics of vivax malaria in Korea: effectiveness of anti-malarial chemoprophylaxis
por: Endo, Akira, et al.
Publicado: (2014)

Malaria burden and anti-malarial drug efficacy in Owando, northern Congo
por: Singana, Brice P., et al.
Publicado: (2016)

Psychiatric effects of malaria and anti-malarial drugs: historical and modern perspectives
por: Nevin, Remington L., et al.
Publicado: (2016)

Battling the malaria iceberg with chloroquine in India
por: Sharma, Vinod P
Publicado: (2007)

The host targeting effect of chloroquine in malaria
por: Coban, Cevayir
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_bc9aps9se030n98b3s39kpsn50