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High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities

Adaptive cellular stress responses are paramount in the healthy control of cell and tissue homeostasis and generally activated during toxicity in a chemical-specific manner. Here, we established a platform containing a panel of distinct adaptive stress response reporter cell lines based on BAC-trans...

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Detalles Bibliográficos
Autores principales: Wink, Steven, Hiemstra, Steven, Herpers, Bram, van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316409/
https://www.ncbi.nlm.nih.gov/pubmed/27358234
http://dx.doi.org/10.1007/s00204-016-1781-0