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High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities
Adaptive cellular stress responses are paramount in the healthy control of cell and tissue homeostasis and generally activated during toxicity in a chemical-specific manner. Here, we established a platform containing a panel of distinct adaptive stress response reporter cell lines based on BAC-trans...
Autores principales: | Wink, Steven, Hiemstra, Steven, Herpers, Bram, van de Water, Bob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316409/ https://www.ncbi.nlm.nih.gov/pubmed/27358234 http://dx.doi.org/10.1007/s00204-016-1781-0 |
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