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Covalent assembly of nanoparticles as a peptidase-degradable platform for molecular MRI

Ligand-conjugated microparticles of iron oxide (MPIO) have the potential to provide high sensitivity contrast for molecular magnetic resonance imaging (MRI). However, the accumulation and persistence of non-biodegradable micron-sized particles in liver and spleen precludes their clinical use and lim...

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Detalles Bibliográficos
Autores principales: Perez-Balderas, Francisco, van Kasteren, Sander I., Aljabali, Alaa A. A., Wals, Kim, Serres, Sébastien, Jefferson, Andrew, Sarmiento Soto, Manuel, Khrapitchev, Alexandre A., Larkin, James R, Bristow, Claire, Lee, Seung Seo, Bort, Guillaume, De Simone, Filippo, Campbell, Sandra J., Choudhury, Robin P., Anthony, Daniel C., Sibson, Nicola R., Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316865/
https://www.ncbi.nlm.nih.gov/pubmed/28198362
http://dx.doi.org/10.1038/ncomms14254