Infection-derived lipids elicit an immune deficiency circuit in arthropods

The insect immune deficiency (IMD) pathway resembles the tumour necrosis factor receptor network in mammals and senses diaminopimelic-type peptidoglycans present in Gram-negative bacteria. Whether unidentified chemical moieties activate the IMD signalling cascade remains unknown. Here, we show that...

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Detalles Bibliográficos
Autores principales: Shaw, Dana K., Wang, Xiaowei, Brown, Lindsey J., Chávez, Adela S. Oliva, Reif, Kathryn E., Smith, Alexis A., Scott, Alison J., McClure, Erin E., Boradia, Vishant M., Hammond, Holly L., Sundberg, Eric J., Snyder, Greg A., Liu, Lei, DePonte, Kathleen, Villar, Margarita, Ueti, Massaro W., de la Fuente, José, Ernst, Robert K., Pal, Utpal, Fikrig, Erol, Pedra, Joao H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316886/
https://www.ncbi.nlm.nih.gov/pubmed/28195158
http://dx.doi.org/10.1038/ncomms14401

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